Searchable abstracts of presentations at key conferences in endocrinology

ea0063gp30 | Diabetes and Cardiovascular Disease | ECE2019

Cardiovascular risk factors in patients with type 2 diabetes and non-alcoholic fat liver disease

Svetlana Rodionova , Elena Birukova , Larisa Zvenigorodskaya

Background and aims: To investigate the level of lipoprotein associated phospholipase A2 (LpPLA2), nitrogen oxide (NO) in patients with type 2 diabetes (DM2) and nonalcoholic fatty liver disease (NAFLD) against a variety of hypoglycemic therapies (HT).Materials and methods: A one-stage examination of 90 patients with DM 2 and NAFLD was carried out. Men ratio 37.8%, women ratio 62.2%, mean age 57.3±11.6 years. Mean HbAlc 7.4±1.82%. According to ...

ea0070ep218 | Diabetes, Obesity, Metabolism and Nutrition | ECE2020

Dynamics of indicators of cytolysis, carbonyl stress in patients with type 2 diabetes and non-alcoholic fatty liver disease on glucose-lowering therapies

Svetlana Rodionova , Larissa Zvenigorodskaya , Elena Biryukova , Alexander Petrakov , Tamara Nilova

Objective: To study the dynamics of cytolysis and carbonyl stress (methylglyoxal (MG)) in patients with type 2 diabetes mellitus (DM2) and non-alcoholic fat disease liver (NAFLD) on the background of various hypoglycemic therapy.Materials and methods: The study included 48 patients, 53.8 ± 11.14 years, with SD2 and NAFLD and 20 people in the control group. Viral hepatitis was excluded, toxic and drug-induced liver injury. Anthropometric researc incl...

ea0063p74 | Calcium and Bone 1 | ECE2019

Multiple fragility fractures in young female patients caused by FGF23-induced hypophoshatemic osteomalacia

Grebennikova Tatiana , Slashchuk Konstantin , Tarbaeva Natalia , Rozhinskaya Liudmila , Rodionova Svetlana , Melnichenko Galina , Rumjantsev Pavel , Belaya Zhanna

Tumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome of abnormal phosphate metabolism caused by a small mesenchymal tumor that secrete fibroblast growth factor 23 (FGF23). A 29-year-old female has suffered from two low-traumatic hip fractures, multiple fractures at the pelvic and sacrum, and diffuse bone pain for more than 3 years. Her mobility was limited in the last year (used crutches) because she had severe muscle weakness. Laboratory examination at the time ...